Description: Oestrogen is a female hormone that helps cells grow and stay alive. It is made in the Those functions are different for men and women. In premenopausal women, less oestrogen means long periods of time when there is little or no vaginal tissue growth, which can lead to painful intercourse, UTIs, and other problems. As estrogen levels fall in postmenopausal women, symptoms worsen, including hot flashes, night sweats, vaginal dryness, and depression.